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Revealing the patterns and determinants of the spread of dengue virus DENV at local scales is central to understanding the epidemiology and evolution of this major human pathogen. We performed a phylogenetic analysis of the envelope E genes of DENV-1, -2, -3, and -4 isolates involving 97, 23, 5, and 74 newly collected sequences, respectively sampled from school-based cohort and village-based cluster studies in Kamphaeng Phet, Thailand, between and With these data, we sought to describe the spatial and temporal patterns of DENV spread within a rural population where a future vaccine efficacy trial is planned. Our analysis revealed considerable genetic diversity within the study population, with multiple lineages within each serotype circulating for various lengths of time during the study period. These results suggest that DENV is frequently introduced into both semi-urban and rural areas in Kamphaeng Phet from other populations. In contrast, the persistence of viral lineages across sampling years was observed less frequently.
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Kamphaeng Phet

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File:Seal Kamphaeng crieffcomedyfest.com - Wikimedia Commons

Thu, May 27 - Fri, May 28 1. The 3-star La Riva Boutique Hotel offers comfort and convenience whether you're on business or holiday in Kamphaengphet. The hotel offers a high standard of service and amenities to suit the individual needs of all travelers. Each guestroom is elegantly furnished and equipped with handy amenities.
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Burmese–Siamese War (1568–1569)

He was often called the Father of the Thai radio and the Father of the Thai railways , due to his contributions in both fields. He was the 35th son of Chulalongkorn and Consort Wat. He received the education in Suankularb Wittayalai School. In , he attended Harrow School , England. And he attended studying in France and Netherlands in the School of engineering of digging dam-canals.
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Thu, 27 May - Fri, 28 May 1. Free private parking is available on site. Stop at Navarat Heritage Hotel to discover the wonders of Kamphaengphet. Both business travelers and tourists can enjoy the hotel's facilities and services. Take advantage of the hotel's executive floor, meeting facilities, restaurant, bicycle rental, smoking area.
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